Anam Ashraf

Dr. Anam Ashraf is currently working as a DHR Young Scientist at the Centre for Interdisciplinary Research in Basic Sciences (CIRBSc), Jamia Millia Islamia (JMI), New Delhi, India. She is currently pursuing a Post-doc in Structural based drug discovery, with research primarily focused on microbial antibiotic resistance. Her areas of interest include X-ray crystallography, computational drug discovery, molecular biology and microbiology. As part of their ongoing research, she is working on a project titled " Structure-Assisted Design of Therapeutics Against Thymidine kinase of Staphylococcus aureus", which aims to elucidate the crystal structure of Thymidine kinase of Staphylococcus aureus and design novel small-molecule inhibitors against it. Dr. Anam has been awarded DBT-BET-JRF fellowship during her Ph.D. They have contributed to scientific literature with several publications.

1.     Ashraf A*, Pal RK, Hassan MI. Crystal structure of thymidine kinase from the multi-drug resistant col strain of Staphylococcus aureus. Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics. 2025 Apr 4:141071.(*Co-corresponding author)

2.     Ashraf A*, Ahmad M, Mariadasse R, Khan MA, Noor S, Islam A, Hassan MI. Integrated spectroscopic and MD simulation approach to decipher the effect of pH on the structure function of Staphylococcus aureus thymidine kinase. Journal of Biomolecular Structure and Dynamics. 2025 Mar 4;43(4):1969-80.(*Co-corresponding author)

3.     Ashraf A, Dwivedy A, Jha B, Kumar D, Agarwal N, Biswal BK. De novo histidine biosynthesis protects Mycobacterium tuberculosis from host IFN-γ mediated histidine starvation. Communications Biology. 2021 Mar 25;4(1):410.