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Projects

Selective Pharmacological Inhibition of the Transcriptional Antiterminator Protein, RfaH of Klebsiella pneumoniae Funded by the Department of Health Research

2020-2023

Funded by the Department of Health Research Ministry of Health, Government of India

(₹64.78 L)

​Identification of MARK 4 inhibitors from bioactive phytoconstituents of Bacopa Monnieri (Brahmi): Therapeutic management of Alzheimer’s disease and neuro-inflammation animal model

2020-2023
Funded by the National Medicinal Plant Board
Ministry of AYUSH, Government of India
(₹22.20 L)

Identification of a high affinity selective inhibitor of calcium/calmodulin-dependent protein kinase IV by a combined experimental and computational approach

2020-2023
Funded by the Indian Council of Medical Research
Ministry of Health, Government of India
(₹52.70 L)

Systems Regulatory Networks of Autophagy Proteins in Leishmania: Implications towards Drug Design (Co-PI)

2020-2023
Funded by the Indian Council of Medical Research
Ministry of Health, Government of India
(₹34.39 L)

Developing small molecule inhibitors to target non-genomic androgen signaling and elucidating the role of GPR56 in Prostate Cancer (Co-PI)

2020-2023
Funded by the Department of Science and Technology
Ministry of Science and Technology, Government of India
(₹43.10 L)

Design & development of SARS-CoV-2 main Protease Inhibitors

2020-2023
Funded by ISTI-CP China

Structure-based Design and Development of Selective Sphingosine Kinase 1 Inhibitors to Combat Idiopathic Pulmonary Fibrosis

2020-2023
Funded by the Indian Council of Medical Research
Ministry of Health, Government of India
(₹36.45 L)

Elucidation of neurodegenerative tauopathies through MARK4 inhibitors: Design and evaluation of MARK4 inhibitors using in silico and in vitro approaches and investigation of their role to cure hyper phosphorylation of tau proteins

2020-2023
Funded by the Indian Council of Medical Research
Ministry of Health, Government of India
(₹56.39 L)

In Silico (Molecular Dynamic Simulation) and In Vitro Approaches to Understand Counteraction of Urea’s Effects on Proteins by Kidney Osmolytes (Co-PI)

2020-2023
Funded by the Indian Council of Medical Research
Ministry of Health, Government of India
(₹46.39 L)

Targeting Alzheimer disease by a mixture of Unani plant extract via modulation of human kinase

2020-2023
Funded by the Central Council for Research in Unani Medicine, Ministry of AYUSH, Government of India
(₹22.10 L)

Development of Pim-1 Kinase-Specific Inhibitors as Preclinical Lead for the Prostate Cancer Therapy

2020-2023
Funded by the Council of Scientific & Industrial Research
Government of India
(₹42.60 L)

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